The coronary arteries are the blood vessels that deliver oxygen-rich blood to the heart. If these arteries become restricted or blocked, you may experience chest pain (angina) or, in time, a heart attack.1
A CABG procedure is performed to relieve chest pain. Successful CABG can improve your course of the disease (prognosis) and provide a better quality of life by lessening pain and disability related to angina.1,2
During the procedure, your surgeon will graft a blood vessel between the aorta (the main blood vessel leaving the heart) and a point along the coronary artery, bypassing the obstructed vessel.2 Donor vessels for the graft can be taken from your leg, inside your chest, or your arm.2 The number of blood vessels grafted will depend on many of your coronary blood vessels have become narrowed or obstructed.3
Your heart will be temporarily stopped using medication while your surgeon performs the bypass surgery, and you may be supported by a heart–lung bypass machine.3 After the grafts have been attached, your heart will be restarted with electrical pulses.3
Reprinted with permission from The Society of Thoracic Surgeons: ctsurgerypatients.org.
During a CABG, your surgeon will bypass an obstructed vessel in order to allow greater blood flow and relief from chest pain3
Aprotinin is a medication used to help reduce blood loss in patients undergoing heart surgery. Aprotinin is licensed in adults undergoing isolated coronary artery bypass graft surgery (CABG).4
After careful consideration of the risks and benefits, your doctor or surgeon has recommended that you would benefit from this treatment because you are at increased risk of major blood loss during your heart surgery.
Aprotinin minimises blood loss during and after your surgery, to reduce the risk of complications, including:
Aprotinin is given into a large blood vessel (intravenously) during your operation.4 The surgical team will monitor the effect of aprotinin throughout your surgery.
Like all medicines, this medicine can cause side effects, although not everybody gets them. Although allergic reactions are rare in patients receiving an aprotinin-containing medicinal product for the first time, patients who are given aprotinin more than once may have an increased chance of an allergic reaction. The symptoms of an allergic reaction may include:
If any of these occur during administration of aprotinin your doctor/surgeon will stop treatment with the drug. Other side effects are:4
|Uncommon: may affect up to 1 in 100 patients||
|Rare: may affect up to 1 in 1,000 patients||
|Very rare: may affect up to 1 in 10,000 patients||
There is a leaflet for patients included in the pack. It contains more information about the medicine. You can find a copy here. If you have any further questions or concerns, please speak to your doctor, surgeon, or pharmacist.